Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers

Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers

Tonic inhibition was imaged in cerebellar granule cells of transgenic mice expressing the optogenetic chloride indicator, Clomeleon. Blockade of GABA A receptors substantially reduced chloride concentration in granule cells due to block of tonic inhibition. This indicates that tonic inhibition is a...

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Bibliographic Details
Main Authors:	Berglund, K., Wen, L., Dunbar, R. L., Feng, G., Augustine, G. J.
Other Authors:	Woods Hole Oceanographic Institution
Format:	Article
Published:	Society for Neuroscience 2017
Online Access:	http://hdl.handle.net/1721.1/112258

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