Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Genetic studies have revealed significant overlaps of risk genes among psychiatric disorders. However, it is not clear how different mutations of the same gene contribute to different disorders. We characterized two lines of mutant mice with Shank3 mutations linked to ASD and schizophrenia. We found...

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Bibliographic Details
Main Authors: Amaya, Aldo, Nguyen, Shannon, Lewis, Michael, Zhou, Yongdi, Zhang, Mingjie, Zhou, Yang, Kaiser, Tobias, Monteiro, Patricia, Zhang, Xiangyu, Van der Goes, Marie-Sophie, Wang, Dongqing, Barak, Boaz, Zeng, Menglong, Li, Chenchen, Lu, Congyi, Wells, Michael, Sanjana, Neville E, Zhang, Feng, Fu, Zhanyan, Feng, Guoping
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Elsevier/Cell Press 2017
Online Access:http://hdl.handle.net/1721.1/112261
https://orcid.org/0000-0002-8665-3912
https://orcid.org/0000-0003-3288-4560
https://orcid.org/0000-0001-9658-0342
https://orcid.org/0000-0001-5251-6664
https://orcid.org/0000-0002-4120-4048
https://orcid.org/0000-0002-3546-4740
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0001-9473-2402
https://orcid.org/0000-0002-8021-277X

Internet

http://hdl.handle.net/1721.1/112261
https://orcid.org/0000-0002-8665-3912
https://orcid.org/0000-0003-3288-4560
https://orcid.org/0000-0001-9658-0342
https://orcid.org/0000-0001-5251-6664
https://orcid.org/0000-0002-4120-4048
https://orcid.org/0000-0002-3546-4740
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0001-9473-2402
https://orcid.org/0000-0002-8021-277X

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