Circuit-Selective Striatal Synaptic Dysfunction in the Sapap3 Knockout Mouse Model of Obsessive-Compulsive Disorder

Circuit-Selective Striatal Synaptic Dysfunction in the Sapap3 Knockout Mouse Model of Obsessive-Compulsive Disorder

Background: Synapse-associated protein 90/postsynaptic density protein 95-associated protein 3 (SAPAP3) is an excitatory postsynaptic protein implicated in the pathogenesis of obsessive-compulsive behaviors. In mice, genetic deletion of Sapap3 causes obsessive-compulsive disorder (OCD)-like behavior...

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Bibliographic Details
Main Authors: Wan, Yehong, Ade, Kristen K., Caffall, Zachary, Ilcim Ozlu, M., Eroglu, Cagla, Feng, Guoping, Calakos, Nicole
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/112272
https://orcid.org/0000-0002-8021-277X

Internet

http://hdl.handle.net/1721.1/112272
https://orcid.org/0000-0002-8021-277X

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