Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Microglia, the tissue-resident macrophages in the brain, are damage sensors that react to nearly any perturbation, including neurodegenerative diseases such as Alzheimer's disease (AD). Here, using single-cell RNA sequencing, we determined the transcriptome of more than 1,600 individual microgl...

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Bibliographic Details
Main Authors: Hemberg, Martin, De Jager, Philip L., Ransohoff, Richard M., Mathys, Hansruedi, Adaikkan, Chinnakkaruppan, Gao, Fan, Young, Jennie Zin-Ney, Manet, Elodie, Regev, Aviv, Tsai, Li-Huei
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/112677
https://orcid.org/0000-0001-5842-5245
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0003-1262-0592

Internet

http://hdl.handle.net/1721.1/112677
https://orcid.org/0000-0001-5842-5245
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0003-1262-0592

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