Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior
Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome (RTT). The RTT missense MECP2 R306C mutation prevents MeCP2 from interacting with the NCoR/histone deacetylase 3 (HDAC3) complex; however, the neuronal function of HDAC3 is incompletely understood. We found that neuronal deletion...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
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Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/112683 https://orcid.org/0000-0002-2029-7193 https://orcid.org/0000-0003-4000-8827 https://orcid.org/0000-0002-2461-1135 https://orcid.org/0000-0002-3255-4740 https://orcid.org/0000-0001-6263-2423 https://orcid.org/0000-0003-1262-0592 |