Efficient derivation of microglia-like cells from human pluripotent stem cells

Microglia, the only lifelong resident immune cells of the central nervous system (CNS), are highly specialized macrophages that have been recognized to have a crucial role in neurodegenerative diseases such as Alzheimer's, Parkinson's and adrenoleukodystrophy (ALD). However, in contrast to...

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Bibliographic Details
Main Authors: Muffat, Julien, Li, Yun, Yuan, Bingbing, Mitalipova, Maisam, Omer, Attya, Bakiasi, Grisilda, Aubourg, Patrick, Ransohoff, Richard M, Corcoran, Sean R., Tsai, Li-Huei, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112684
https://orcid.org/0000-0003-1262-0592