Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment

Cyclin-dependent kinase 5 (Cdk5) is associated with synaptic plasticity and cognitive function. Previous reports have demonstrated that Cdk5 is necessary for memory formation, although others have reported Cdk5 conditional knockout mouse models exhibiting enhanced learning and memory. Furthermore, h...

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Bibliographic Details
Main Authors: Su, Susan Chih-Chieh, Rudenko, Andrii, Cho, Sukhee, Tsai, Li-Huei
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/112703
https://orcid.org/0000-0003-1262-0592