Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment
Cyclin-dependent kinase 5 (Cdk5) is associated with synaptic plasticity and cognitive function. Previous reports have demonstrated that Cdk5 is necessary for memory formation, although others have reported Cdk5 conditional knockout mouse models exhibiting enhanced learning and memory. Furthermore, h...
Principais autores: | , , , |
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Outros Autores: | |
Formato: | Artigo |
Publicado em: |
Elsevier
2017
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Acesso em linha: | http://hdl.handle.net/1721.1/112703 https://orcid.org/0000-0003-1262-0592 |