Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment

Cyclin-dependent kinase 5 (Cdk5) is associated with synaptic plasticity and cognitive function. Previous reports have demonstrated that Cdk5 is necessary for memory formation, although others have reported Cdk5 conditional knockout mouse models exhibiting enhanced learning and memory. Furthermore, h...

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Detalhes bibliográficos
Principais autores: Su, Susan Chih-Chieh, Rudenko, Andrii, Cho, Sukhee, Tsai, Li-Huei
Outros Autores: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Formato: Artigo
Publicado em: Elsevier 2017
Acesso em linha:http://hdl.handle.net/1721.1/112703
https://orcid.org/0000-0003-1262-0592