Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment
Cyclin-dependent kinase 5 (Cdk5) is associated with synaptic plasticity and cognitive function. Previous reports have demonstrated that Cdk5 is necessary for memory formation, although others have reported Cdk5 conditional knockout mouse models exhibiting enhanced learning and memory. Furthermore, h...
Main Authors: | Su, Susan Chih-Chieh, Rudenko, Andrii, Cho, Sukhee, Tsai, Li-Huei |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Published: |
Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/112703 https://orcid.org/0000-0003-1262-0592 |
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