Multidimensional chemical control of CRISPR–Cas9

Cas9-based technologies have transformed genome engineering and the interrogation of genomic functions, but methods to control such technologies across numerous dimensions-including dose, time, specificity, and mutually exclusive modulation of multiple genes-are still lacking. We conferred such mult...

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Bibliographic Details
Main Authors: Maji, Basudeb, Shoulders, Matthew D, Choudhary, Amit, Moore, Christopher, Zetsche, Bernd, Volz, Sara E., Zhang, Feng
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112729
https://orcid.org/0000-0003-2782-2509