Nucleic acid detection with CRISPR-Cas13a/C2c2

Nucleic acid detection with CRISPR-Cas13a/C2c2

Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. The RNA-guided, RNA-targeting clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas13a (previously known as C2c2) exhibits a "collater...

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Bibliographic Details
Main Authors: Lee, Jeong Wook, Essletzbichler, Patrick, Verdine, Vanessa, Donghia, Nina, Freije, Catherine A., Myhrvold, Cameron, Bhattacharyya, Roby P., Livny, Jonathan, Koonin, Eugene V., Pardis, C. Sabeti, Gootenberg, Jonathan S, Dy, Aaron James, Joung, Julia, Daringer, Nichole Marie, Regev, Aviv, Hung, Deborah T, Collins, James J., Zhang, Feng, Abudayyeh, Omar O.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/112745
https://orcid.org/0000-0002-7979-3220
https://orcid.org/0000-0003-0319-5416
https://orcid.org/0000-0001-6656-5002
https://orcid.org/0000-0002-2026-8130
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0003-2782-2509

Internet

http://hdl.handle.net/1721.1/112745
https://orcid.org/0000-0002-7979-3220
https://orcid.org/0000-0003-0319-5416
https://orcid.org/0000-0001-6656-5002
https://orcid.org/0000-0002-2026-8130
https://orcid.org/0000-0001-8567-2049
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0003-2782-2509

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