Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
Forward genetic screens are powerful tools for the unbiased discovery and functional characterization of specific genetic elements associated with a phenotype of interest. Recently, the RNA-guided endonuclease Cas9 from the microbial CRISPR (clustered regularly interspaced short palindromic repeats)...
| Main Authors: | , , , , , , , |
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| Format: | Article |
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Springer Nature
2017
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| Online Access: | http://hdl.handle.net/1721.1/112748 https://orcid.org/0000-0001-6656-5002 https://orcid.org/0000-0001-7915-1685 https://orcid.org/0000-0002-7979-3220 https://orcid.org/0000-0003-2782-2509 |