Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

While distinct stem cell phenotypes follow global changes in chromatin marks, single-cell chromatin technologies are unable to resolve or predict stem cell fates. We propose the first such use of optical high content nanoscopy of histone epigenetic marks (epi-marks) in stem cells to classify emergen...

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Bibliographic Details
Main Authors: Kim, Joseph J., Bennett, Neal K., Devita, Mitchel S., Chahar, Sanjay, Viswanath, Satish, Lee, Eunjee A., Shao, Paul P., Childers, Erin P., Liu, Shichong, Garcia, Benjamin A., Becker, Matthew L., Hwang, Nathaniel S., Madabhushi, Anant, Verzi, Michael P., Moghe, Prabhas V., Jung, Giyoung, Kulesa, Anthony Benjamin
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112780
https://orcid.org/0000-0003-2834-430X
https://orcid.org/0000-0001-9927-9715