Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

While distinct stem cell phenotypes follow global changes in chromatin marks, single-cell chromatin technologies are unable to resolve or predict stem cell fates. We propose the first such use of optical high content nanoscopy of histone epigenetic marks (epi-marks) in stem cells to classify emergen...

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Detalhes bibliográficos
Principais autores: Kim, Joseph J., Bennett, Neal K., Devita, Mitchel S., Chahar, Sanjay, Viswanath, Satish, Lee, Eunjee A., Shao, Paul P., Childers, Erin P., Liu, Shichong, Garcia, Benjamin A., Becker, Matthew L., Hwang, Nathaniel S., Madabhushi, Anant, Verzi, Michael P., Moghe, Prabhas V., Jung, Giyoung, Kulesa, Anthony Benjamin
Outros Autores: Harvard University--MIT Division of Health Sciences and Technology
Formato: Artigo
Publicado em: Nature Publishing Group 2017
Acesso em linha:http://hdl.handle.net/1721.1/112780
https://orcid.org/0000-0003-2834-430X
https://orcid.org/0000-0001-9927-9715