Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the zygote. How these two epigenetically distinct...
Principais autores: | , , , , , , , , |
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Formato: | Artigo |
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Nature Publishing Group
2017
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Acesso em linha: | http://hdl.handle.net/1721.1/112793 https://orcid.org/0000-0002-5320-2728 https://orcid.org/0000-0001-5814-0864 https://orcid.org/0000-0002-0785-5410 |