Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the zygote. How these two epigenetically distinct...

ver descrição completa

Detalhes bibliográficos
Principais autores: Flyamer, Ilya M., Gassler, Johanna, Brandão, Hugo B., Ulianov, Sergey V., Razin, Sergey V., Tachibana-Konwalski, Kikuë, Imakaev, Maksim Viktorovich, Abdennur, Nezar Alexander, Mirny, Leonid A
Outros Autores: Institute for Medical Engineering and Science
Formato: Artigo
Publicado em: Nature Publishing Group 2017
Acesso em linha:http://hdl.handle.net/1721.1/112793
https://orcid.org/0000-0002-5320-2728
https://orcid.org/0000-0001-5814-0864
https://orcid.org/0000-0002-0785-5410