History of chromosome rearrangements reflects the spatial organization of yeast chromosomes

Three-dimensional (3D) organization of genomes affects critical cellular processes such as transcription, replication, and deoxyribo nucleic acid (DNA) repair. While previous studies have investigated the natural role, the 3D organization plays in limiting a possible set of genomic rearrangements fo...

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Bibliographic Details
Main Authors: Khrameeva, Ekaterina E., Gelfand, Mikhail S., Fudenberg, Geoffrey, Mirny, Leonid A
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Published: World Scientific Publishing 2017
Online Access:http://hdl.handle.net/1721.1/112796
https://orcid.org/0000-0001-5905-6517
https://orcid.org/0000-0002-0785-5410