Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register

Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register

The yeast prion protein Sup35NM is a self-propagating amyloid. Despite intense study, there is no consensus on the organization of monomers within Sup35NM fibrils. Some studies point to a â-helical arrangement, whereas others suggest a parallel inregister organization. Intermolecular contacts are of...

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Bibliographic Details
Main Authors: Frederick, Kendra K., Caporini, Marc A., Michaelis, Vladimir K., Andreas, Loren, Lindquist, Susan, Debelouchina, Galia Tzvetanova, Griffin, Robert Guy
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Proceedings of the National Academy of Sciences 2017
Online Access:http://hdl.handle.net/1721.1/112944
https://orcid.org/0000-0002-6708-7660
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0003-1589-832X

Internet

http://hdl.handle.net/1721.1/112944
https://orcid.org/0000-0002-6708-7660
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0003-1589-832X

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