A Population Dynamics Model for Clonal Diversity in a Germinal Center

A Population Dynamics Model for Clonal Diversity in a Germinal Center

Germinal centers (GCs) are micro-domains where B cells mature to develop high affinity antibodies. Inside a GC, B cells compete for antigen and T cell help, and the successful ones continue to evolve. New experimental results suggest that, under identical conditions, a wide spectrum of clonal divers...

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Bibliographic Details
Main Authors: Mesin, Luka, Victora, Gabriel D., Amitai, Assaf, Kardar, Mehran, Chakraborty, Arup K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: Frontiers Research Foundation 2017
Online Access:http://hdl.handle.net/1721.1/112995
https://orcid.org/0000-0002-8594-6529
https://orcid.org/0000-0002-1112-5912
https://orcid.org/0000-0003-1268-9602

Internet

http://hdl.handle.net/1721.1/112995
https://orcid.org/0000-0002-8594-6529
https://orcid.org/0000-0002-1112-5912
https://orcid.org/0000-0003-1268-9602

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