A Population Dynamics Model for Clonal Diversity in a Germinal Center
Germinal centers (GCs) are micro-domains where B cells mature to develop high affinity antibodies. Inside a GC, B cells compete for antigen and T cell help, and the successful ones continue to evolve. New experimental results suggest that, under identical conditions, a wide spectrum of clonal divers...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
Frontiers Research Foundation
2017
|
| Online Access: | http://hdl.handle.net/1721.1/112995 https://orcid.org/0000-0002-8594-6529 https://orcid.org/0000-0002-1112-5912 https://orcid.org/0000-0003-1268-9602 |