Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways interact to maintain homeostasis in proliferating...

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Bibliographic Details
Main Authors: Hung, Yin P, Teragawa, Carolyn, Kosaisawe, Nont, Gillies, Taryn E, Pargett, Michael, Minguet, Marta, Distor, Kevin, Rocha-Gregg, Briana L, Coloff, Jonathan L, Yellen, Gary, Brugge, Joan S, Albeck, John G, Keibler, Mark Andrew, Stephanopoulos, Gregory
Format: Article
Published: eLife Sciences Publications, Ltd 2018
Online Access:http://hdl.handle.net/1721.1/113029
https://orcid.org/0000-0002-5410-6543
https://orcid.org/0000-0001-6909-4568

Internet

http://hdl.handle.net/1721.1/113029
https://orcid.org/0000-0002-5410-6543
https://orcid.org/0000-0001-6909-4568

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