Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells
Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways interact to maintain homeostasis in proliferating...
Main Authors: | Hung, Yin P, Teragawa, Carolyn, Kosaisawe, Nont, Gillies, Taryn E, Pargett, Michael, Minguet, Marta, Distor, Kevin, Rocha-Gregg, Briana L, Coloff, Jonathan L, Yellen, Gary, Brugge, Joan S, Albeck, John G, Keibler, Mark Andrew, Stephanopoulos, Gregory |
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Format: | Article |
Published: |
eLife Sciences Publications, Ltd
2018
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Online Access: | http://hdl.handle.net/1721.1/113029 https://orcid.org/0000-0002-5410-6543 https://orcid.org/0000-0001-6909-4568 |
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