Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB

In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of DNA ends by a helicase-nuclease complex such as AddAB. The activity of AddAB has been well-studied in vitro, with translocation speeds between...

Full description

Bibliographic Details
Main Authors: Badrinarayanan, Anjana, Le, Tung, Spille, Jan Hendrik, Cisse, Ibrahim I, Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Public Library of Science (PLoS) 2018
Online Access:http://hdl.handle.net/1721.1/113234
https://orcid.org/0000-0002-6807-6576
https://orcid.org/0000-0003-4764-8851
https://orcid.org/0000-0001-8493-4721
https://orcid.org/0000-0002-8764-1809
https://orcid.org/0000-0002-8288-7607