Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB
In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of DNA ends by a helicase-nuclease complex such as AddAB. The activity of AddAB has been well-studied in vitro, with translocation speeds between...
Main Authors: | Badrinarayanan, Anjana, Le, Tung, Spille, Jan Hendrik, Cisse, Ibrahim I, Laub, Michael T |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
Public Library of Science (PLoS)
2018
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Online Access: | http://hdl.handle.net/1721.1/113234 https://orcid.org/0000-0002-6807-6576 https://orcid.org/0000-0003-4764-8851 https://orcid.org/0000-0001-8493-4721 https://orcid.org/0000-0002-8764-1809 https://orcid.org/0000-0002-8288-7607 |
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