Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Small molecule screens are widely used to prioritize pharmaceuti...

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Bibliographic Details
Main Authors: Beeharry, Neil, Fink, Lauren, Bhattacharjee, Vikram, Huang, Shao-shan Carol, Zhou, Yan, Yen, Tim, Ursu, Oana, Gosline, Sara Calafell, Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Public Library of Science 2018
Online Access:http://hdl.handle.net/1721.1/113260
https://orcid.org/0000-0002-6534-4774
https://orcid.org/0000-0001-9249-8181