Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling

Metabolism is an emerging stem cell hallmark tied to cell fate, pluripotency, and self-renewal, yet systems-level understanding of stem cell metabolism has been limited by the lack of genome-scale network models. Here, we develop a systems approach to integrate time-course metabolomics data with a c...

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Bibliographic Details
Main Authors: Chandrasekaran, Sriram, Zhang, Jin, Sun, Zhen, Zhang, Li, Ross, Christian A., Huang, Yu-Chung, Asara, John M., Li, Hu, Daley, George Q., Collins, James J.
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/113270
https://orcid.org/0000-0002-6897-2135
https://orcid.org/0000-0002-5560-8246