Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling
Metabolism is an emerging stem cell hallmark tied to cell fate, pluripotency, and self-renewal, yet systems-level understanding of stem cell metabolism has been limited by the lack of genome-scale network models. Here, we develop a systems approach to integrate time-course metabolomics data with a c...
Main Authors: | Chandrasekaran, Sriram, Zhang, Jin, Sun, Zhen, Zhang, Li, Ross, Christian A., Huang, Yu-Chung, Asara, John M., Li, Hu, Daley, George Q., Collins, James J. |
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Other Authors: | Institute for Medical Engineering and Science |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/113270 https://orcid.org/0000-0002-6897-2135 https://orcid.org/0000-0002-5560-8246 |
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