Alpha2delta-1 in SF1⁺ Neurons of the Ventromedial Hypothalamus Is an Essential Regulator of Glucose and Lipid Homeostasis

The central mechanisms controlling glucose and lipid homeostasis are inadequately understood. We show that α2δ-1 is an essential regulator of glucose and lipid balance, acting in steroidogenic factor-1 (SF1) neurons of the ventromedial hypothalamus (VMH). These effects are body weight independent an...

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Bibliographic Details
Main Authors: Felsted, Jennifer A., Chien, Cheng-Hao, Wang, Dongqing, Panessiti, Micaella, Ameroso, Dominique, Greenberg, Andrew, Feng, Guoping, Kong, Dong, Rios, Maribel
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/113272
https://orcid.org/0000-0002-8021-277X