Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors

Metal-free magnetic resonance imaging (MRI) agents could overcome the established toxicity associated with metal-based agents in some patient populations and enable new modes of functional MRI in vivo. Herein, we report nitroxide-functionalized brush-arm star polymer organic radical contrast agents...

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Bibliographic Details
Main Authors: Paletta, Joseph T., Zhang, Hui, Boska, Michael D., Ottaviani, M. Francesca, Rajca, Andrzej, Nguyen, Hung VanThanh, Chen, Qixian, Harvey, Peter, Jiang, Yivan, Jasanoff, Alan Pradip, Johnson, Jeremiah A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/113328
https://orcid.org/0000-0002-6945-4057
https://orcid.org/0000-0002-8163-7059
https://orcid.org/0000-0002-2834-6359
https://orcid.org/0000-0001-9157-6491