High-Affinity Manganese Coordination by Human Calprotectin Is Calcium-Dependent and Requires the Histidine-Rich Site Formed at the Dimer Interface

High-Affinity Manganese Coordination by Human Calprotectin Is Calcium-Dependent and Requires the Histidine-Rich Site Formed at the Dimer Interface

Zobrazit další vydání (1)

Calprotectin (CP) is a transition metal-chelating antimicrobial protein of the calcium-binding S100 family that is produced and released by neutrophils. It inhibits the growth of various pathogenic microorganisms by sequestering the transition metal ions manganese and zinc. In this work, we investig...

Celý popis

Podrobná bibliografie
Hlavní autoři: Hayden, Joshua A., Brophy, Megan Brunjes, Cunden, Lisa Stephanie, Nolan, Elizabeth Marie
Další autoři: Massachusetts Institute of Technology. Department of Chemistry
Médium: Článek
Vydáno: American Chemical Society (ACS) 2018
On-line přístup:http://hdl.handle.net/1721.1/113554
https://orcid.org/0000-0002-1733-9874
https://orcid.org/0000-0002-6153-8803

Internet

http://hdl.handle.net/1721.1/113554
https://orcid.org/0000-0002-1733-9874
https://orcid.org/0000-0002-6153-8803

Podobné jednotky