Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this process is known to be regulated by follicular helper T (TfH) cells, the mechanism by which B cells initially seed ge...

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Bibliographic Details
Main Authors: Gaya, Mauro, Barral, Patricia, Burbage, Marianne, Aggarwal, Shweta, Montaner, Beatriz, Warren Navia, Andrew, Aid, Malika, Tsui, Carlson, Maldonado, Paula, Nair, Usha, Ghneim, Khader, Fallon, Padraic G., Sekaly, Rafick-Pierre, Barouch, Dan H., Bruckbauer, Andreas, Strid, Jessica, Batista, Facundo D., Shalek, Alexander K
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/113555