Oil Palm Phenolics Inhibit the n Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes

Alzheimer’s disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the soluble oligomers of Aβ42 are neurotoxic and proinflammato...

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Bibliographic Details
Main Authors: Tan, Yew Ai, Sambanthamurthi, Ravigadevi, Weinberg, Robert P, Koledova, Vera V, Shin, Alice Hyeari, Park, Jennifer, Sinskey, Anthony J, Rha, Chokyun
Other Authors: Massachusetts Institute of Technology. Biomaterials Science and Engineering Laboratory
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2018
Online Access:http://hdl.handle.net/1721.1/113590
https://orcid.org/0000-0002-1015-1270
https://orcid.org/0000-0002-6671-5987