Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis
Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...
Main Authors: | , , , , , , , , , |
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Other Authors: | |
Format: | Article |
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Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/113595 https://orcid.org/0000-0003-3623-3968 https://orcid.org/0000-0001-9451-2194 |