Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...

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Bibliographic Details
Main Authors: Mori, Munemasa, Mahoney, John E., Li, Huijun, Lu, Jining, Zhu, Xueliang, Cardoso, Wellington V., Hazan, Renin, Miller, Emily Sun Young, Lees, Jacqueline, Danielian, Paul S.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/113595
https://orcid.org/0000-0003-3623-3968
https://orcid.org/0000-0001-9451-2194