Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis
Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...
| Main Authors: | , , , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
Nature Publishing Group
2018
|
| Online Access: | http://hdl.handle.net/1721.1/113595 https://orcid.org/0000-0003-3623-3968 https://orcid.org/0000-0001-9451-2194 |