The m⁶A Pathway Facilitates Sex Determination in Drosophila

The m⁶A Pathway Facilitates Sex Determination in Drosophila

The conserved modification N⁶-methyladenosine (m⁶A) modulates mRNA processing and activity. Here, we establish the Drosophila system to study the m⁶A pathway. We first apply miCLIP to map m 6 A across embryogenesis, characterize its m⁶A 'writer' complex, validate its YTH 'readers'...

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Bibliographic Details
Main Authors: Kan, Lijuan, Grozhik, Anya V., Vedanayagam, Jeffrey, Patil, Deepak P., Pang, Nan, Huang, Yi-Chun, Joseph, Brian, Lin, Ching-Jung, Despic, Vladimir, Guo, Jian, Yan, Dong, Kondo, Shu, Deng, Wu-Min, Jaffrey, Samie R., Lai, Eric C., Lim, Kok Seong, Dedon, Peter C
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/113617
https://orcid.org/0000-0003-0011-3067

Internet

http://hdl.handle.net/1721.1/113617
https://orcid.org/0000-0003-0011-3067

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