DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase

DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying difficult DNA and incorporating non-natural dNTPs, due to their l...

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Bibliographic Details
Main Authors: Wu, Jing, de Paz, Alexandra, Zamft, Bradley M., Marblestone, Adam H., Kording, Konrad P., Tyo, Keith E. J., Boyden, Edward
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/113619
https://orcid.org/0000-0002-0419-3351

Internet

http://hdl.handle.net/1721.1/113619
https://orcid.org/0000-0002-0419-3351

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