Mechanistic action of weak acid drugs on biofilms

Mechanistic action of weak acid drugs on biofilms

Selective permeability of a biofilm matrix to some drugs has resulted in the development of drug tolerant bacteria. Here we studied the efficacy of a weak organic acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of Pseudomonas aeruginosa and investigat...

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Bibliographic Details
Main Authors: Kundukad, Binu, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Schussman, Megan K., Doyle, Patrick S
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/113621
https://orcid.org/0000-0003-2147-9172

Internet

http://hdl.handle.net/1721.1/113621
https://orcid.org/0000-0003-2147-9172

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