Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Nucleic acid therapeutics are limited by inefficient delivery to target tissues and cells and by an incomplete understanding of how nanoparticle structure affects biodistribution to off-target organs. Although thousands of nanoparticle formulations have been designed to deliver nucleic acids, most n...

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Bibliographic Details
Main Authors: Kauffman, Kevin John, Xing, Yiping, Shaw, Taylor E., Mir, Faryal, Dlott, Chloe C., Langer, Robert S, Anderson, Daniel Griffith, Wang, Eric T, Dahlman, James E.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/113871
https://orcid.org/0000-0002-9436-2453
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

Internet

http://hdl.handle.net/1721.1/113871
https://orcid.org/0000-0002-9436-2453
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

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