Encounter times of chromatin loci influenced by polymer decondensation

The time for a DNA sequence to find its homologous counterpart depends on a long random search inside the cell nucleus. Using polymer models, we compute here the mean first encounter time (MFET) between two sites located on two different polymer chains and confined locally by potential wells. We fin...

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Bibliographic Details
Main Authors: Holcman, D., Amitai, Assaf
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:English
Published: American Physical Society 2018
Online Access:http://hdl.handle.net/1721.1/114509
https://orcid.org/0000-0002-8594-6529