Encounter times of chromatin loci influenced by polymer decondensation

The time for a DNA sequence to find its homologous counterpart depends on a long random search inside the cell nucleus. Using polymer models, we compute here the mean first encounter time (MFET) between two sites located on two different polymer chains and confined locally by potential wells. We fin...

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Detalles Bibliográficos
Main Authors: Holcman, D., Amitai, Assaf
Outros autores: Institute for Medical Engineering and Science
Formato: Artigo
Idioma:English
Publicado: American Physical Society 2018
Acceso en liña:http://hdl.handle.net/1721.1/114509
https://orcid.org/0000-0002-8594-6529