An Engineered Synthetic Pathway for Discovering Nonnatural Nonribosomal Peptides in Escherichia coli

Peptides that are synthesized independently of the ribosome in plants, fungi, and bacteria can have clinically relevant anticancer, antihemochromatosis, and antiviral activities, among many other. Despite their natural origin, discovering new natural products is challenging, and there is a need to e...

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Bibliographic Details
Main Authors: Lu, Timothy K, Cleto, Sara
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: American Society for Microbiology 2018
Online Access:http://hdl.handle.net/1721.1/114599
https://orcid.org/0000-0002-9999-6690