Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and

Vaccines have had broad medical impact, but existing vaccine technologies and production methods are limited in their ability to respond rapidly to evolving and emerging pathogens, or sudden outbreaks. Here, we develop a rapid-response, fully synthetic, singledose, adjuvant-free dendrimer nanopartic...

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Bibliographic Details
Main Authors: Chahal, Jasdave S., Cooper, Christopher L., McPartlan, Justine S., Tilley, Lucas D., Sidik, Saima M., Lourido, Sebastian, Bavari, Sina, Ploegh, Hidde L., Khan, Omar Fizal, Tsosie, Jonathan, Langer, Robert S, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/114728
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798