Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
Gene expression heterogeneity in the pluripotent state of mouse embryonic stem cells (mESCs) has been increasingly well-characterized. In contrast, exit from pluripotency and lineage commitment have not been studied systematically at the single-cell level. Here we measure the gene expression dynamic...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
Nature Publishing Group
2018
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| Online Access: | http://hdl.handle.net/1721.1/114774 |