Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects

Diverse molecular mechanisms regulate synaptic composition and function in the mammalian nervous system. The multifunctional protein arginine methyltransferase 8 (PRMT8) possesses both methyltransferase and phospholipase activities. Here we examine the role of this neuron-specific protein in hippoca...

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Bibliographic Details
Main Authors: Penney, Jay, Seo, Jinsoo, Kritskiy, Oleg, Elmsaouri, Sara, Gao, Fan, Pao, Ping-Chieh, Su, Susan Chih-Chieh, Tsai, Li-Huei
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Society for Neuroscience 2018
Online Access:http://hdl.handle.net/1721.1/114826
https://orcid.org/0000-0001-5607-113X
https://orcid.org/0000-0001-6788-7185
https://orcid.org/0000-0003-1262-0592