Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects
Diverse molecular mechanisms regulate synaptic composition and function in the mammalian nervous system. The multifunctional protein arginine methyltransferase 8 (PRMT8) possesses both methyltransferase and phospholipase activities. Here we examine the role of this neuron-specific protein in hippoca...
Main Authors: | Penney, Jay, Seo, Jinsoo, Kritskiy, Oleg, Elmsaouri, Sara, Gao, Fan, Pao, Ping-Chieh, Su, Susan Chih-Chieh, Tsai, Li-Huei |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Published: |
Society for Neuroscience
2018
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Online Access: | http://hdl.handle.net/1721.1/114826 https://orcid.org/0000-0001-5607-113X https://orcid.org/0000-0001-6788-7185 https://orcid.org/0000-0003-1262-0592 |
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