SMC complexes differentially compact mitotic chromosomes according to genomic context

Structural maintenance of chromosomes (SMC) protein complexes are key determinants of chromosome conformation. Using Hi-C and polymer modelling, we study how cohesin and condensin, two deeply conserved SMC complexes, organize chromosomes in the budding yeast Saccharomyces cerevisiae. The canonical r...

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Bibliographic Details
Main Authors: Schalbetter, Stephanie Andrea, Belton, Jon-Matthew, Miles, Catrina, Yu, Miao, Dekker, Job, Baxter, Jonathan, Goloborodko, Anton, Fudenberg, Geoffrey, Mirny, Leonid A
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/114831
https://orcid.org/0000-0002-2210-8616
https://orcid.org/0000-0001-5905-6517
https://orcid.org/0000-0002-0785-5410