Convergent and Biomimetic Enantioselective Total Synthesis of (−)-Communesin F

The first biomimetic enantioselective total synthesis of (-)-communesin F based on a late-stage heterodimerization and aminal exchange is described. Our synthesis features the expedient diazene-directed assembly of two advanced fragments to secure the congested C3a-C3a′ linkage in three steps, follo...

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Bibliographic Details
Main Authors: Lathrop, Stephen, Pompeo, Matthew M, Chang, Wen-Tau, Movassaghi, Mohammad
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/114840
https://orcid.org/0000-0001-7761-085X
https://orcid.org/0000-0001-5955-7653
https://orcid.org/0000-0003-3080-1063