Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality
Downstream metabolic events can contribute to the lethality of drugs or agents that interact with a primary cellular target. In bacteria, the production of reactive oxygen species (ROS) has been associated with the lethal effects of a variety of stresses including bactericidal antibiotics, but the r...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
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National Academy of Sciences (U.S.)
2018
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| Online Access: | http://hdl.handle.net/1721.1/114885 https://orcid.org/0000-0002-7127-9833 https://orcid.org/0000-0003-0921-4657 https://orcid.org/0000-0003-4710-1389 https://orcid.org/0000-0002-5560-8246 https://orcid.org/0000-0001-7243-8261 |