Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

Brain tumor-initiating cells (BTICs) have been identified as key contributors to therapy resistance, recurrence, and progression of diffuse gliomas, particularly glioblastoma (GBM). BTICs are elusive therapeutic targets that reside across the blood–brain barrier, underscoring the urgent need to deve...

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Bibliographic Details
Main Authors: Yu, Dou, Suvà, Mario L., Dong, Biqin, Panek, Wojciech K., Xiao, Ting, Wu, Meijing, Han, Yu, Ahmed, Atique U., Balyasnikova, Irina V., Zhang, Hao F., Sun, Cheng, Lesniak, Maciej S., Khan, Omar Fizal, Langer, Robert S, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/114893
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

Internet

http://hdl.handle.net/1721.1/114893
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

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