Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow

Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its interactions with recruited platelets and leukocytes determine disease progression. Here, we report widespread changes in alternative splicing of...

全面介绍

书目详细资料
Main Authors: Kimble, Amy L., Murphy, Patrick A., Butty, Vincent L. G., Boutz, Paul, Begum, Shahinoor, Sharp, Phillip A., Burge, Christopher B., Hynes, Richard O.
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
出版: eLife Sciences Publications, Ltd 2018
在线阅读:http://hdl.handle.net/1721.1/114943
https://orcid.org/0000-0003-0788-3136
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0001-7603-8396