Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow

Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow

Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its interactions with recruited platelets and leukocytes determine disease progression. Here, we report widespread changes in alternative splicing of...

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Bibliographic Details
Main Authors:	Kimble, Amy L., Murphy, Patrick A., Butty, Vincent L. G., Boutz, Paul, Begum, Shahinoor, Sharp, Phillip A., Burge, Christopher B., Hynes, Richard O.
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Published:	eLife Sciences Publications, Ltd 2018
Online Access:	http://hdl.handle.net/1721.1/114943 https://orcid.org/0000-0003-0788-3136 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0001-7603-8396

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