Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

The RNA-guided endonuclease Cas9 generates a double-strand break at DNA target sites complementary to the guide RNA and has been harnessed for the development of a variety of new technologies, such as genome editing. Here, we report the crystal structures of Campylobacter jejuni Cas9 (CjCas9), one o...

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Bibliographic Details
Main Authors: Yamada, Mari, Watanabe, Yuto, Hirano, Hisato, Ran, F. Ann, Nakane, Takanori, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nureki, Osamu, Gootenberg, Jonathan S, Zhang, Feng
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/114953
https://orcid.org/0000-0003-2782-2509

Internet

http://hdl.handle.net/1721.1/114953
https://orcid.org/0000-0003-2782-2509

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