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Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

Hydroxyurea (HU) has been used clinically to reduce the frequency of painful crisis and the need for blood transfusion in sickle cell disease (SCD) patients. However, the mechanisms underlying such beneficial effects of HU treatment are still not fully understood. Studies have indicated a weak corre...

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Bibliographic Details
Main Authors: Hosseini, Poorya, Abidi, Sabia Z., Du, E, Papageorgiou, Dimitrios P., Choi, Youngwoon, Higgins, John M., Kato, Gregory J., Suresh, Subra, Dao, Ming, Yaqoob, Zahid, So, Peter T. C., Park, YongKeun, Ph.D. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/114975
https://orcid.org/0000-0001-7347-7887
https://orcid.org/0000-0003-2678-4491
https://orcid.org/0000-0001-5372-385X
https://orcid.org/0000-0003-4698-6488
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http://hdl.handle.net/1721.1/114975
https://orcid.org/0000-0001-7347-7887
https://orcid.org/0000-0003-2678-4491
https://orcid.org/0000-0001-5372-385X
https://orcid.org/0000-0003-4698-6488

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