Detection of Copy Number Alterations Using Single Cell Sequencing
Detection of genomic changes at single cell resolution is important for characterizing genetic heterogeneity and evolution in normal tissues, cancers, and microbial populations. Traditional methods for assessing genetic heterogeneity have been limited by low resolution, low sensitivity, and/or low s...
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Format: | Article |
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MyJoVE Corporation
2018
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Online Access: | http://hdl.handle.net/1721.1/115000 https://orcid.org/0000-0003-0649-7428 https://orcid.org/0000-0002-0989-8115 |